Antibacterial Antibiotics in General Practice

  • KV Krishna Das, B.Sc, MBBS, FRCP (E), DTM & H, FAMS Medical College, Trivandrum; IMA Member.
Keywords: Antibiotics, Mechanism of action, Adverse effects, Development of antibiotic resistance

Abstract

This detailed review deals with the general aspects of the therapeutics of antibiotics in common use for bacterial infections, with emphasis on those more frequently employed by the family physicians in India.
Since almost all of them are metabolic poisons, they also lead to cellular damage in the host to varying degrees. Therefore adverse side effects are almost universal , the type and severity of the adverse effects varying among the different drugs.
Exposure to antibiotics leads to the proliferation of resistant mutants. This results in ineffectiveness of the drug in the same patients and in those others who get infection from such patients. This problem is probably the most important adverse effect on a community level:
All the common antibiotics used are reviewed.
The antibacterial antibiotic armamentarium is quite well equipped. Judicious selection by the physician is absolutely essential for effectiveness, safety and avoidance of adverse effects. It is also essential that the practicing physician keeps himself abreast of modern developments which aim at fine- tuning the treatment of infective diseases.

Author Biography

KV Krishna Das, B.Sc, MBBS, FRCP (E), DTM & H, FAMS, Medical College, Trivandrum; IMA Member.

Retired Director and Professor of Medicine

Published
2010-06-29
How to Cite
Das, K. (2010). Antibacterial Antibiotics in General Practice. Kerala Medical Journal, 3(2), 64-75. https://doi.org/10.52314/kmj.2010.v3i2.172
Section
Drug Profile