Advances in the Management of Type 2 Diabetes Mellitus
Abstract
Diabetes mellitus is a chronic metabolic disorder of the endocrine system, characterized by a complex and varied pathophysiology. Worldwide, there is a dramatic increase in the number of patients with type 2 diabetes, and hence it is becoming a serious threat to the health of mankind. Commercially, a large number of drugs belonging to different classes, such as the Insulins, biguanides, sulfonylureas, meglitinides, and thiazolidinediones, DPP-4 inhibitors, SGLT2 INHIBITORS, and GLP1 AGONISTS are available to control and treat type 2 diabetic patients. However, none of these drugs are known to cure the diabetic phenotype completely. Furthermore, some of these agents can cause weight gain and have a limited role in the later stages of the disease. Newer formulations are reaching the market, which will help manage T2DM and improve patient outcomes.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
When publishing with Kerala Medicial Journal (KMJ), authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. Work includes the material submitted for publication and any other related material submitted to KMJ. In the event that KMJ does not publish said work, the author(s) will be so notified and all rights assigned hereunder will revert to the author(s).
The assignment of rights to KMJ includes but is not expressly limited to rights to edit, publish, reproduce, distribute copies, include in indexes or search databases in print, electronic, or other media, whether or not in use at the time of execution of this agreement.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
The author(s) hereby represents and warrants that they are sole author(s) of the work, that all authors have participated in and agree with the content and conclusions of the work, that the work is original, and does not infringe upon any copyright, propriety, or personal right of any third party, and that no part of it nor any work based on substantially similar data has been submitted to another publication.
