A Rare Case of Anti-Phospholipid Antibody Syndrome with Bleeding Manifestation

  • P Baburaj Jubilee Mission Medical College & Research Institute, East Fort, Thrissur, Kerala - 680005.
  • B V Shankara Assistant Professor, Jubilee Mission Medical College & Research Institute, East Fort, Thrissur, Kerala - 680005.
  • Nadeemu Rahman Jubilee Mission Medical College & Research Institute, East Fort, Thrissur, Kerala - 680005
Keywords: Antiphospholipid Syndrome, Anti-prothrombin Antibodies, Lupus Anticoagulant

Abstract

The Antiphospholipid syndrome or Antiphospholipid antibody syndrome (APS or APLS), is an acquired autoimmune thrombophilic disorder in which patient have vascular thrombosis and/or pregnancy complications attributable to placental insufficiency accompanied by presence of anti-phospholipid antibodies in blood. Bleeding manifestations are uncommon in APS. Prolongation of aPTT is an usual manifestation of APS but not accounting for any bleeding manifestations. In rare occasions, a hemorrhagic diathesis can occur due to the occurrence of anti-prothrombin antibodies causing severe hypoprothrombinemia.
We are reporting a case Antiphospholipid Syndrome with rare atypical bleeding manifestations.

Author Biographies

P Baburaj, Jubilee Mission Medical College & Research Institute, East Fort, Thrissur, Kerala - 680005.

MD, Professor of Medicine & Unit Head

B V Shankara, Assistant Professor, Jubilee Mission Medical College & Research Institute, East Fort, Thrissur, Kerala - 680005.

MBBS DNB, Department of Medicine

Nadeemu Rahman, Jubilee Mission Medical College & Research Institute, East Fort, Thrissur, Kerala - 680005

Post Graduate, Dept.of Medicine

Published
2017-06-30
How to Cite
Baburaj, P., Shankara, B., & Rahman, N. (2017). A Rare Case of Anti-Phospholipid Antibody Syndrome with Bleeding Manifestation. Kerala Medical Journal, 10(2), 92-94. https://doi.org/10.52314/kmj.2017.v10i2.81
Section
Case Series / Case Report